Impact of CCR2 and SDF1 polymorphisms on disease progression in HIV-infected subjects in Thailand.

doi:10.1002/jcla.21559

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Article

Impact of CCR2 and SDF1 polymorphisms on disease progression in HIV-infected subjects in Thailand.

Journal of clinical laboratory analysis - 1 Jan 2013

Ammaranond Palanee, Sanguansitthianan Sayompoo, Phaengchomduan Poonlaph, Sae-Lee Chanachai, Mardkhumchan Sirimarn

Abstract excerpt

BACKGROUND: The genotypic polymorphisms of CCR5, CCR2, and SDF1 were analyzed to determine their impact as potential confounders with regard to disease progression because of the role that host genetic factors appear to be involved in determining rates of disease progression. METHODS: Genomic DNA was extracted from Ethylenediaminetetraacetate whole blood using Qiagen DNA extraction kit. The amplification of CCR5,...

Topics

Adult
Aged
CD4 Lymphocyte Count
Chemokine CXCL12
Chi-Square Distribution
Disease Progression
Female
HIV Infections
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Receptors, CCR2

Receptors, CCR5

Statistics, Nonparametric

Source

Open in PubMed Open full text

Identifiers

PMID: 23325742
DOI: 10.1002/jcla.21559
PMCID: PMC6807585

Genes

CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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