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Article

Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium.

Infection and immunity - 1 Dec 2002

Tamayo Rita, Ryan Sara S, McCoy Andrea J, Gunn John S

Abstract excerpt

Salmonella enterica serovar Typhimurium encounters antimicrobial peptides (AP) within the phagosomes of professional phagocytes and at intestinal mucosal surfaces. Salmonella serovar Typhimurium utilizes the two-component regulatory system PmrA-PmrB, which is activated in response to the environmental conditions encountered in vivo, to regulate resistance to several AP, including polymyxin B (PM). Random MudJ...

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Source

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Identifiers

PMID: 12438352
DOI: 10.1128/IAI.70.12.6770-6778.2002
PMCID: PMC133008

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