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Article

Association of TGFB1 29C/T and IL6 -572G/C polymorphisms with developmental hip dysplasia: a case-control study in adults with severe osteoarthritis.

International orthopaedics - 1 Apr 2015

Čengić Tomislav, Trkulja Vladimir, Pavelić Sandra Kraljević, Ratkaj Ivana, Markova-Car Elitza, Mikolaučić Michele, Kolundžić Robert

Abstract excerpt

PURPOSE: Developmental dysplasia of the hip (DDH) increases the risk of severe adult hip osteoarthritis (OA). Transforming growth factor-β1 (TGF-beta1) and interleukin-6 (IL-6) are included in pathogenesis of OA, as well as in development of the musculoskeletal system. We investigated the association of single nucleotide polymorphisms (SNPs) known to reflect on the circulating levels of the two cytokines,...

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Share to Aged, 80 and over
Share to Arthroplasty, Replacement, Hip

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hip Dislocation, Congenital

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Source

Identifiers

PMID: 25603974
DOI: 10.1007/s00264-015-2675-0

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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