Article
Genetic study identifies novel genes in developmental dysplasia of the hip.
Bone research - 31 Mar 2026
Yoshino Soichiro, Chen Shibo, Yamaguchi Ryosuke, Kurakazu Taishi, Hatzikotoulas Konstantinos, Koike Yoshinao, Inoue Daisuke, Kohno Yusuke, Sasaki Kan, Choe Hyonmin, Baba Shoji, Hara Toshihiko, Ito Juji, Okuzu Yaichiro, Shiomoto Kyohei, Nakamura Tomoyuki, Koyano Gaku, Shimizu Tomohiro, Kinoshita Koichi, Takahashi Eiji, Utsunomiya Takeshi, Hara Daisuke, Sato Taishi, Kawahara Shinya, Kaneuji Ayumi, Yamamoto Takuaki, Takahashi Daisuke, Jinno Tetsuya, Kawano Tsutomu, Goto Koji, Takagi Michiaki, Mawatari Taro, Inaba Yutaka, Nakamura Tetsuro, Kabata Tamon, Hamai Satoshi, Motomura Goro, Southam Lorraine, Wilkinson J Mark, Zeggini Eleftheria, Ikegawa Shiro, Nakashima Yasuharu, Terao Chikashi
Abstract excerpt
Developmental dysplasia of the hip (DDH), a morphological abnormality of the hip joint, is a well-recognized risk factor for hip osteoarthritis (OA). Much remains unknown about the genetic factors of DDH and its subtypes. To further understand its genetic basis, we conducted genome-wide association studies (GWASs) using a total of 1 085 Japanese DDH cases (including 788 hip dysplasia cases without dislocation and...
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