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Article

Genetic Study of IL6, GDF5 and PAPPA2 in Association with Developmental Dysplasia of the Hip.

Genes - 28 Jun 2021

Harsanyi Stefan, Zamborsky Radoslav, Krajciova Lubica, Kokavec Milan, Danisovic Lubos

Abstract excerpt

BACKGROUND: Developmental dysplasia of the hip (DDH) is one of the most prevalent skeletal disorders. DDH is considered a pathologic condition with polygenic background, but environmental and mechanic factors significantly contribute to its multifactorial etiology. Inheritance consistent with autosomal dominant type has also been observed. Single-nucleotide polymorphisms (SNPs) in various genes mostly related to...

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PMID: 34203285
DOI: 10.3390/genes12070986
PMCID: PMC8303839

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Source receipt: pubmed, retrieved 7 Sept 2026.

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