Article
C-reactive protein polymorphisms influence serum CRP-levels independent of disease activity in ankylosing spondylitis.
Clinical and experimental rheumatology - 1 Jan 2000
Claushuis Theodora A M, de Vries Mirjam K, van der Weijden Mignon A C, Visman Ingrid M, Nurmohamed Michael T, Twisk Jos W R, Van der Horst-Bruinsma Irene E, Crusius Jakob B A
Abstract excerpt
OBJECTIVES: C-reactive protein (CRP) levels are frequently used to determine disease activity in patients with ankylosing spondylitis (AS), but these levels may not reflect disease activity. We therefore investigated the influence of common single-nucleotide polymorphisms (SNPs) in the CRP gene on CRP levels in AS patients. Additionally, the relation between CRP levels and BASDAI (Bath Ankylosing Spondylitis...
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