Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C-reactive protein gene variants: independent association with late-life depression and circulating protein levels.

Translational psychiatry - 20 Jan 2015

Ancelin M-L, Farré A, Carrière I, Ritchie K, Chaudieu I, Ryan J

Abstract excerpt

C-reactive protein (CRP) is a heritable biomarker of systemic inflammation that is commonly elevated in depressed patients. Variants in the CRP gene that influence protein levels could thus be associated with depression but this has seldom been examined, especially in the elderly. Depression was assessed in 990 people aged at least 65 years as part of the ESPRIT study. A clinical level of depression (DEP) was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Aged
Share to Antidepressive Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Depressive Disorder

Share to Depressive Disorder, Major

Share to Multivariate Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25603415
DOI: 10.1038/tp.2014.145
PMCID: PMC4312833

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C-reactive protein gene variants: independent association with late-life depression and circulating protein levels.PMID 25603415Read ↗

Polymorphisms in the CRP gene moderate an association between depressive symptoms and circulating levels of C-reactive protein.Semantic proximity Read ↗

Elevated C-Reactive Protein in Patients With Depression, Independent of Genetic, Health, and Psychosocial Factors: Results From the UK Biobank.Semantic proximity Read ↗

Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study.Semantic proximity Read ↗

Elevated C-reactive protein, depression, somatic diseases, and all-cause mortality: a mendelian randomization study.Semantic proximity Read ↗

Relationship between polymorphism rs2794521 in CRP gene and survival of depressive patients with chronic heart failure.Semantic proximity Read ↗

Genetic Contributions of Inflammation to DepressionSemantic proximity Read ↗

Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP studySemantic proximity Read ↗

DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorderSemantic proximity Read ↗

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive SymptomsSemantic proximity Read ↗

Treatment-resistant depression and peripheral C-reactive protein.Semantic proximity Read ↗

C-reactive protein (CRP) gene polymorphisms, CRP levels, and risk of incident coronary heart disease in two nested case-control studies.Semantic proximity Read ↗

Genetic susceptibility, inflammation and specific types of depressive symptoms: evidence from the English Longitudinal Study of Ageing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.