Article
Stopping ovarian cancer screening in BRCA1/2 mutation carriers: effects on risk management decisions & outcome of risk-reducing salpingo-oophorectomy specimens.
Maturitas - 1 Mar 2015
van Driel Catheleine M G, de Bock Geertruida H, Arts Henriette J G, Sie Aisha S, Hollema Harry, Oosterwijk Jan C, Mourits Marian J E
Abstract excerpt
OBJECTIVE: Ovarian cancer screening (OCS) for BRCA1/2 mutation carriers was stopped in our family cancer clinic in 2009 because of its ineffectiveness. The study objective was to investigate the effect of stopping OCS on the timing and uptake of risk-reducing salpingo-oophorectomy (RRSO) and on the percentage of occult cancers in the specimens. METHODS: 419 BRCA1/2 mutation carriers were recruited between January...
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