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Article

Cannabis, Cannabinoids, and the Endocannabinoid System-Is there Therapeutic Potential for Inflammatory Bowel Disease?

Journal of Crohn's & colitis - 30 Mar 2019

Ambrose Tim, Simmons Alison

Abstract excerpt

Cannabis sativa and its extracts have been used for centuries, both medicinally and recreationally. There is accumulating evidence that exogenous cannabis and related cannabinoids improve symptoms associated with inflammatory bowel disease [IBD], such as pain, loss of appetite, and diarrhoea. In vivo, exocannabinoids have been demonstrated to improve colitis, mainly in chemical models. Exocannabinoids signal...

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Identifiers

PMID: 30418525
DOI: 10.1093/ecco-jcc/jjy185
PMCID: PMC6441301

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