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Article

Associations between DNA methylation and schizophrenia-related intermediate phenotypes - a gene set enrichment analysis.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2015

Hass Johanna, Walton Esther, Wright Carrie, Beyer Andreas, Scholz Markus, Turner Jessica, Liu Jingyu, Smolka Michael N, Roessner Veit, Sponheim Scott R, Gollub Randy L, Calhoun Vince D, Ehrlich Stefan

Abstract excerpt

Multiple genetic approaches have identified microRNAs as key effectors in psychiatric disorders as they post-transcriptionally regulate expression of thousands of target genes. However, their role in specific psychiatric diseases remains poorly understood. In addition, epigenetic mechanisms such as DNA methylation, which affect the expression of both microRNAs and coding genes, are critical for our understanding...

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Identifiers

PMID: 25598502
DOI: 10.1016/j.pnpbp.2015.01.006
PMCID: PMC4346504

Genes

EPHA4
ESR1
PKNOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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