Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histology-directed and imaging mass spectrometry: An emerging technology in ectopic calcification.

Bone - 1 May 2015

Taverna Domenico, Boraldi Federica, De Santis Giorgio, Caprioli Richard M, Quaglino Daniela

Abstract excerpt

The present study was designed to demonstrate the potential of an optimized histology directed protein identification combined with imaging mass spectrometry technology to reveal and identify molecules associated to ectopic calcification in human tissue. As a proof of concept, mineralized and non-mineralized areas were compared within the same dermal tissue obtained from a patient affected by Pseudoxanthoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcification, Physiologic
Share to Calcinosis
Share to Diagnostic Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Ontology

Share to Principal Component Analysis

Share to Protein Interaction Maps

Share to Pseudoxanthoma Elasticum

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Open in PubMed Open full text

Identifiers

PMID: 25595835
DOI: 10.1016/j.bone.2015.01.004
PMCID: PMC4355241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histology-directed and imaging mass spectrometry: An emerging technology in ectopic calcification.PMID 25595835Read ↗

Insights into Pathomechanisms and Treatment Development in Heritable Ectopic Mineralization Disorders: Summary of the PXE International Biennial Research Symposium-2016.Semantic proximity Read ↗

Unraveling the Human Bone Microenvironment beyond the Classical Extracellular Matrix Proteins: A Human Bone Protein LibrarySemantic proximity Read ↗

Ectopic mineralization disorders of the extracellular matrix of connective tissue: molecular genetics and pathomechanisms of aberrant calcification.Semantic proximity Read ↗

Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls.Semantic proximity Read ↗

Matrix Metalloproteinases Contribute to the Calcification Phenotype in Pseudoxanthoma Elasticum.Semantic proximity Read ↗

Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticumSemantic proximity Read ↗

Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labellingSemantic proximity Read ↗

Pseudoxanthoma elasticum, the paradigm of heritable ectopic mineralization disorders - can diet help?Semantic proximity Read ↗

Inorganic Pyrophosphate Plasma Levels Are Decreased in Pseudoxanthoma Elasticum Patients and Heterozygous Carriers but Do Not Correlate with the Genotype or PhenotypeSemantic proximity Read ↗

Correlation of systemic involvement and presence of pathological skin calcification assessed by ex vivo nonlinear microscopy in Pseudoxanthoma elasticum.Semantic proximity Read ↗

Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach.Semantic proximity Read ↗

Mineralization of the connective tissue: a complex molecular process leading to age-related loss of function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.