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Article

Mineralization of the connective tissue: a complex molecular process leading to age-related loss of function.

Rejuvenation research - 1 Apr 2014

Shindyapina Anastasia V, Mkrtchyan Garik V, Gneteeva Tatiana, Buiucli Sveatoslav, Tancowny B, Kulka M, Aliper Alexander, Zhavoronkov Alexander

Abstract excerpt

Age-related metastatic mineralization of soft tissues has been considered a passive and spontaneous process. Recent data have demonstrated that calcium salt deposition in soft tissues could be a highly regulated process. Although calcification occurs in any tissue type, vascular calcification has been of particular interest due to association with atherosclerosis, chronic kidney disease (CKD), and osteoporosis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23902273
DOI: 10.1089/rej.2013.1475

Genes

FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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