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Article

iPINBPA: an integrative network-based functional module discovery tool for genome-wide association studies.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2015

Wang Lili, Mousavi Parvin, Baranzini Sergio E

Abstract excerpt

We introduce the integrative protein-interaction-network-based pathway analysis (iPINBPA) for genome-wide association studies (GWAS), a method to identify and prioritize genetic associations by merging statistical evidence of association with physical evidence of interaction at the protein level. First, the strongest associations are used to weight all nodes in the PPI network using a guilt- by-association...

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PMID: 25592586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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