Article
The challenges of liver transplantation in children with primary sclerosing cholangitis.
Expert review of gastroenterology & hepatology - 1 Mar 2015
Venkat Veena L, Ranganathan Sarangarajan, Sindhi Rakesh
Abstract excerpt
Primary sclerosing cholangitis (PSC) in children can progress to end-stage liver disease requiring liver transplantation. PSC poses many challenges beginning with evaluation and classification of ductal involvement and overlap syndromes, few options for medical management and unique risks in the post-transplant period. The construct that PSC may be an autoimmune disease is based on positive autoantibodies,...
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