Article
The Childhood Liver Disease Research Network's prospective characterization of pediatric primary sclerosing cholangitis.
Hepatology communications - 1 Oct 2026
Mack Cara L, Miethke Alexander G, Hawthorne Kieran, Henn Lisa, Horslen Simon, Alonso Estella M, Gupta Nitika A, Sundaram Shikha S, Kohli Rohit, Bozic Molly, Deneau Mark, Guthery Stephen, Loomes Kathleen M, Valentino Pamela L, Tessier Mary Elizabeth M, Shneider Benjamin, Magee John C, Karpen Saul, Rosenthal Phillip, Wang Kasper, Ricciuto Amanda, Sokol Ronald J, Kamath Binita M
Abstract excerpt
BACKGROUND: Primary sclerosing cholangitis (PSC) is a rare biliary fibrosing disease that leads to significant morbidity and the need for liver transplantation. The Childhood Liver Disease Research Network is conducting a prospective, observational longitudinal study to define the natural history of pediatric PSC. The aim of this report is to characterize the clinical phenotypes of the first 175 children enrolled...
Read the complete abstract on PubMedTopics
- Humans
- Cholangitis, Sclerosing
- Male
- Prospective Studies