Article
The Natural History of Primary Sclerosing Cholangitis in Children: A Large Single-Center Longitudinal Cohort Study.
Journal of pediatric gastroenterology and nutrition - 1 Dec 2016
Valentino Pamela L, Wiggins Shanna, Harney Sarah, Raza Roshan, Lee Christine K, Jonas Maureen M
Abstract excerpt
OBJECTIVES: Data regarding pediatric primary sclerosing cholangitis (PSC) natural history are limited. We describe a large pediatric PSC cohort with longitudinal follow-up. METHODS: The present study records review of pediatric patients with PSC diagnosed between 1984 and 2014. RESULTS: N = 120 (63% M) ages 1 to 21 years (median 14 years) at diagnosis. 27% (31/113) had autoimmune sclerosing cholangitis (ASC), 24%...
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