Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.

Anatolian journal of cardiology - 1 Oct 2015

Uluçay Safiye, Çam Fethi Sırrı, Batır Muhammed Burak, Sütçü Recep, Bayturan Özgür, Demircan Kadir

Abstract excerpt

OBJECTIVE: Coronary artery disease is characterized by atherosclerosis in the vessel wall. Recently, it has been thought that increasing LDL-binding capacity of subendothelial proteoglycan fragments that are formed by protease activity can be responsible for the initiation of atherosclerosis. ADAMTS4 is a member of the versican-degrading proteinases. In vitro studies demonstrated that TGFb inhibits the expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Disease Progression

Share to Enzyme-Linked Immunosorbent Assay

Share to ROC Curve

Share to Severity of Illness Index

Share to Transforming Growth Factor beta1

Source

Open in PubMed Open full text

Identifiers

PMID: 25592103
DOI: 10.5152/akd.2014.5762
PMCID: PMC5336969

Genes

ADAMTS4
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes.PMID 25592103Read ↗

TGF-β and atherosclerosis in manSemantic proximity Read ↗

Genetic variants of ADAM17 are implicated in the pathological process of Kawasaki disease and secondary coronary artery lesions via the TGF-β/SMAD3 signaling pathway.Semantic proximity Read ↗

Interaction between gene polymorphisms in MLL3 gene and TGF-β signal pathway with the susceptibility of type B aortic dissection in the Chinese populationSemantic proximity Read ↗

Contribution of ADAM17 and related ADAMs in cardiovascular diseasesSemantic proximity Read ↗

Polymorphisms of TGFβ-1 and TGFBR2 in relation to coronary artery disease in a Chinese population.Semantic proximity Read ↗

TGFB1 genetic polymorphisms and coronary heart disease risk: a meta-analysis.Semantic proximity Read ↗

Emerging roles for the ADAMTS-like family of matricellular proteins in cardiovascular disease through regulation of the extracellular microenvironmentSemantic proximity Read ↗

Association between the C804A polymorphism in the TGF-β gene and the risk of myocardial infarction: a meta-analysis.Semantic proximity Read ↗

The Role of ADAM17 in Inflammation-Related AtherosclerosisSemantic proximity Read ↗

The rs3825807 Polymorphism of ADAMTS7 as a Potential Genetic Marker for Myocardial Infarction in Slovenian Subjects with Type 2 Diabetes Mellitus.Semantic proximity Read ↗

ADAMTS7: a Novel Therapeutic Target in AtherosclerosisSemantic proximity Read ↗

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.