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Article

Highly sensitive and noninvasive detection of epidermal growth factor receptor T790M mutation in non-small cell lung cancer.

Clinica chimica acta; international journal of clinical chemistry - 21 Oct 2013

He Chen, Zheng Lixia, Xu Yuzhong, Liu Ming, Li Yuanguang, Xu Jun

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) T790M mutation is associated with EGFR tyrosine kinase inhibitors resistance in non-small cell lung cancer (NSCLC). However, the tissue availability and technical feasibility limits the genotyping of EGFR T790M mutation in the clinical setting. The current study is, therefore, designed to develop a blood-based approach to detect the EGFR T790M mutation in...

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Identifiers

PMID: 23886554
DOI: 10.1016/j.cca.2013.07.012

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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