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Article

A Rapid and Sensitive Method for Detection of the T790M Mutation of EGFR in Plasma DNA.

Advances in experimental medicine and biology - 1 Jan 2016

Kimura Hideharu, Nishikawa Shingo, Koba Hayato, Yoneda Taro, Sone Takashi, Kasahara Kazuo

Abstract excerpt

Epidermal growth factor receptor (EGFR) T790M mutation is associated with resistance to EGFR tyrosine kinase inhibitors' (EGFR-TKIs) in non-small cell lung cancer (NSCLC). The aims of this study are to develop a blood-based, non-invasive approach to detecting the EGFR T790M mutation in advanced NSCLC patients, using PointMan™ EGFR DNA Enrichment Kit which is a novel method for selective amplification of genotype...

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Share to Carcinoma, Non-Small-Cell Lung
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Source

Identifiers

PMID: 27753039
DOI: 10.1007/978-3-319-42044-8_31

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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