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Article

Two-dye based arrayed primer extension for simultaneous multigene detection in lipid metabolism.

Clinica chimica acta; international journal of clinical chemistry - 10 Mar 2015

Jeenduang Nutjaree, Porntadavity Sureerut, von Nickisch-Rosenegk Markus, Bier Frank F, Promptmas Chamras

Abstract excerpt

BACKGROUND: Cardiovascular disease (CVD) is one of the major causes of death worldwide. Numerous genetic risk factors in lipid metabolism, including mutations of LDLR, APOB, and PCSK9, as well as polymorphisms of CETP and APOE, have been found to associate with CVD. METHODS: In this study, a two-dye based arrayed primer extension (APEX) microarray assay for simultaneous multigene (LDLR, APOB, PCSK9, CETP, and...

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Source

Identifiers

PMID: 25591965
DOI: 10.1016/j.cca.2015.01.005

Genes

APOB
APOE
CETP
LDLR
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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