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Article

Single nucleotide polymorphism in Ag85 genes of Mycobacterium tuberculosis complex: analysis of 178 clinical isolates from China and 13 BCG strains.

International journal of medical sciences - 1 Jan 2015

Jiang Yi, Liu Haican, Li Machao, Li Guilian, Pang Hui, Dou Xiangfeng, Zhao Xiuqin, Wan Kanglin

Abstract excerpt

Host immune pressure and associated immune evasion of pathogenic bacteria are key features of host-pathogen co-evolution. Human T-cell epitopes of Mycobacterium tuberculosis (M. tuberculosis) were evolutionarily hyperconserved and thus it was deduced that M. tuberculosis lacks antigenic variation and immune evasion. However, in our previous studies, proteins MPT64, PstS1, Rv0309 and Rv2945c all harbored higher...

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Identifiers

PMID: 25589888
DOI: 10.7150/ijms.9951
PMCID: PMC4293177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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