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Article

Polymorphism of antigen MPT64 in Mycobacterium tuberculosis strains.

Journal of clinical microbiology - 1 May 2013

Jiang Yi, Liu Haican, Wang Haiyin, Dou Xiangfeng, Zhao Xiuqin, Bai Yun, Wan Li, Li Guilian, Zhang Wen, Chen Chen, Wan Kanglin

Abstract excerpt

We selected 180 clinical isolates of the Mycobacterium tuberculosis complex (MTBC) from patients in China and performed comparative sequence analysis of the mpt64 gene after amplification. From the results, we found that polymorphisms of the mpt64 gene in the MTBC may be the reason for changes in the antigen produced, which may in turn cause alterations of related functions, thereby allowing immune evasion.

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Share to Mycobacterium tuberculosis
Share to Antigens, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Evasion

Share to Nucleic Acid Amplification Techniques

Share to Protein Structure, Tertiary

Share to Sequence Analysis, DNA

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Source

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Identifiers

PMID: 23390287
DOI: 10.1128/JCM.02955-12
PMCID: PMC3647925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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