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Article

Overexpression of isocitrate dehydrogenase-1R¹³²H enhances the proliferation of A172 glioma cells via aerobic glycolysis.

Molecular medicine reports - 1 May 2015

Nie Quanmin, Guo Pin, Guo Liemei, Lan Jin, Lin Yingying, Guo Fang, Zhou Sunhai, Ge Jianwei, Mao Qing, Li Xiaoxiong, Qiu Yongming

Abstract excerpt

Gliomas are the most common type of primary malignancy of the central nervous system. The identification of mutations in the gene encoding isocitrate dehydrogenase‑1 (IDH1) represents a key area of investigation in studies on glioma. The IDH1R132H mutation is a heterozygous point mutation, which...

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Source

Identifiers

PMID: 25586175
DOI: 10.3892/mmr.2015.3187

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25586175-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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