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Article

CHEK2 mutations and the risk of papillary thyroid cancer.

International journal of cancer - 1 Aug 2015

Siołek Monika, Cybulski Cezary, Gąsior-Perczak Danuta, Kowalik Artur, Kozak-Klonowska Beata, Kowalska Aldona, Chłopek Małgorzata, Kluźniak Wojciech, Wokołorczyk Dominika, Pałyga Iwona, Walczyk Agnieszka, Lizis-Kolus Katarzyna, Sun Ping, Lubiński Jan, Narod Steven A, Góźdż Stanisław

Abstract excerpt

Mutations in the cell cycle checkpoint kinase 2 (CHEK2) tumor suppressor gene are associated with multi-organ cancer susceptibility including cancers of the breast and prostate. A genetic association between thyroid and breast cancer has been suggested, however little is known about the determinants of this association. To characterize the association of CHEK2 mutations with thyroid cancer, we genotyped 468...

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Source

Identifiers

PMID: 25583358
DOI: 10.1002/ijc.29426

Genes

CHEK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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