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Article

Profiling of ubiquitination pathway genes in peripheral cells from patients with frontotemporal dementia due to C9ORF72 and GRN mutations.

International journal of molecular sciences - 8 Jan 2015

Serpente Maria, Fenoglio Chiara, Cioffi Sara M G, Bonsi Rossana, Arighi Andrea, Fumagalli Giorgio G, Ghezzi Laura, Scarpini Elio, Galimberti Daniela

Abstract excerpt

We analysed the expression levels of 84 key genes involved in the regulated degradation of cellular protein by the ubiquitin-proteasome system in peripheral cells from patients with frontotemporal dementia (FTD) due to C9ORF72 and GRN mutations, as compared with sporadic FTD and age-matched contr...

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Identifiers

PMID: 25580532
DOI: 10.3390/ijms16011385
PMCID: PMC4307308

Genes

GRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25580532-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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