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Article

A gene expression phenotype in lymphocytes from Friedreich ataxia patients.

Annals of neurology - 1 Nov 2011

Coppola Giovanni, Burnett Ryan, Perlman Susan, Versano Revital, Gao Fuying, Plasterer Heather, Rai Myriam, Saccá Francesco, Filla Alessandro, Lynch David R, Rusche James R, Gottesfeld Joel M, Pandolfo Massimo, Geschwind Daniel H

Abstract excerpt

OBJECTIVE: Gene expression studies in peripheral tissues from patients with neurodegenerative disorders can provide insights into disease pathogenesis, and identify potential biomarkers, an important goal of translational research in neurodegeneration. Friedreich Ataxia (FRDA) is a chronic neurodegenerative disease caused by reduced transcription of frataxin, a ubiquitously expressed protein. We studied in vitro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22162061
DOI: 10.1002/ana.22526
PMCID: PMC3646419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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