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Cerebral gene expression profiles in sporadic Creutzfeldt–Jakob disease

27 Jul 2005

Abstract excerpt

The pathomechanism of sporadic Creutzfeldt-Jakob disease (sCJD) in the central nervous system is insufficiently understood. The aims of this study were to identify differentially regulated genes in the frontal cortex of sCJD and to profile the gene expression patterns in sCJD by using Affymetrix HGU133A microarrays (Affymetrix, Santa Clara, CA). The microarray data were generated by dChip and analyzed by...

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PMID: 16049922
DOI: 10.1002/ana.20551

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