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Article

Pharmacological characterization of [3H]VUF11211, a novel radiolabeled small-molecule inverse agonist for the chemokine receptor CXCR3.

Molecular pharmacology - 1 Apr 2015

Scholten Danny J, Wijtmans Maikel, van Senten Jeffrey R, Custers Hans, Stunnenberg Ailas, de Esch Iwan J P, Smit Martine J, Leurs Rob

Abstract excerpt

Chemokine receptor CXCR3 has attracted much attention, as it is thought to be associated with a wide range of immune-related diseases. As such, several small molecules with different chemical structures targeting CXCR3 have been discovered. Despite limited clinical success so far, these compounds serve as interesting tools for investigating receptor activation and antagonism. Accumulating evidence suggests that...

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Source

Identifiers

PMID: 25576486
DOI: 10.1124/mol.114.095265

Genes

CXCR3
CXCL11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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