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Article

Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors.

Molecular pharmacology - 1 Dec 2008

Wong Rebecca S Y, Bodart Veronique, Metz Markus, Labrecque Jean, Bridger Gary, Fricker Simon P

Abstract excerpt

CXC chemokine receptor (CXCR)4 is an HIV coreceptor and a chemokine receptor that plays an important role in several physiological and pathological processes, including hematopoiesis, leukocyte homing and trafficking, metastasis, and angiogenesis. This receptor belongs to the class A family of G protein-coupled receptors and is a validated target for the development of a new class of antiretroviral therapeutics....

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Identifiers

PMID: 18768385
DOI: 10.1124/mol.108.049775

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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