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Article

Identification of allosteric peptide agonists of CXCR4.

The Journal of biological chemistry - 10 Jan 2003

Sachpatzidis Aristidis, Benton Benjamin K, Manfredi John P, Wang Hua, Hamilton Andrew, Dohlman Henrik G, Lolis Elias

Abstract excerpt

The chemokine receptor CXCR4 is a co-receptor for T-tropic strains of HIV-1. A number of small molecule antagonists of CXCR4 are in development but all are likely to lead to adverse effects due to the physiological function of CXCR4. To prevent these complications, allosteric agonists may be ther...

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Source

Identifiers

PMID: 12417595
DOI: 10.1074/jbc.M204667200

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12417595-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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