Article
Association of Toll like receptor Asp299Gly with rheumatoid arthritis risk: a systematic review of case-control studies and meta-analysis.
Pathology, research and practice - 1 Mar 2015
Tizaoui Kalthoum, Naouali Abir, Kaabachi Wajih, Hamzaoui Agnès, Hamzaoui Kamel
Abstract excerpt
OBJECTIVE: Rheumatoid arthritis (RA) is thought to be triggered by various genetic and environmental factors. Few human epidemiologic studies demonstrated that single nucleotide polymorphisms (SNPs) in Toll-like receptor (TLR) genes are associated with RA. We aimed to evaluate the effects of TLR polymorphisms on the risk of RA pathogenesis by using a meta-analysis approach. METHODS: Following the Preferred...
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