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Article

Multiplex screening of 22 single-nucleotide polymorphisms in 7 Toll-like receptors: an association study in rheumatoid arthritis.

The Journal of rheumatology - 1 May 2010

Enevold Christian, Radstake Timothy R D, Coenen Marieke J H, Fransen Jaap, Toonen Erik J M, Bendtzen Klaus, van Riel Piet L C M

Abstract excerpt

OBJECTIVE: Toll-like receptors (TLR) have been implicated in the pathogenesis of arthritis. We investigated the role of functional variants of TLR in the disease phenotype and severity of rheumatoid arthritis (RA). METHODS: All patients from a longterm observational inception cohort (n = 319) wer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20194452
DOI: 10.3899/jrheum.090775

Genes

TLR2
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20194452-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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