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Article

No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.

Arthritis research & therapy - 1 Jan 2009

Jaen Olivier, Petit-Teixeira Elisabeth, Kirsten Holger, Ahnert Peter, Semerano Luca, Pierlot Céline, Cornelis Francois, Boissier Marie-Christophe, Falgarone Geraldine

Abstract excerpt

INTRODUCTION: The objective was to study the potential genetic contribution of Toll-like receptor (TLR) genes in rheumatoid arthritis (RA). TLRs bind to pathogen-associated molecular patterns, and TLR genes influence both proinflammatory cytokine production and autoimmune responses. Host-pathogen interactions are involved in RA physiopathology. METHODS: We tested SNPs of five TLR genes (TLR9, TLR2, TLR6, TLR1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19134200
DOI: 10.1186/ar2589
PMCID: PMC2688235

Genes

TLR2
TLR9
TLR1
TLR6
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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