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Article

BSSV: Bayesian based somatic structural variation identification with whole genome DNA-seq data.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2014

Chen Xi, Shi Xu, Shajahan Ayesha N, Hilakivi-Clarke Leena, Clarke Robert, Xuan Jianhua

Abstract excerpt

High coverage whole genome DNA-sequencing enables identification of somatic structural variation (SSV) more evident in paired tumor and normal samples. Recent studies show that simultaneous analysis of paired samples provides a better resolution of SSV detection than subtracting shared SVs. However, available tools can neither identify all types of SSVs nor provide any rank information regarding their somatic...

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PMID: 25570853
DOI: 10.1109/EMBC.2014.6944485
PMCID: PMC4492453

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