Article

Comprehensive analysis of structural variants in breast cancer genomes using single molecule sequencing

2019-11-19

Abstract excerpt

Improved identification of structural variants (SVs) in cancer can lead to more targeted and effective treatment options as well as advance our basic understanding of disease progression. We performed whole genome sequencing of the SKBR3 breast cancer cell-line and patient-derived tumor and normal organoids from two breast cancer patients using 10X/Illumina, PacBio, and Oxford Nanopore sequencing. We then inferred...

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Literature Corpus work: c6e461c1-3f2b-528d-8b9c-d63b5d4ea202
DOI: 10.1101/847855

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