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Article

CRF-amplified neuronal TLR4/MCP-1 signaling regulates alcohol self-administration.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 May 2015

June Harry L, Liu Juan, Warnock Kaitlin T, Bell Kimberly A, Balan Irina, Bollino Dominique, Puche Adam, Aurelian Laure

Abstract excerpt

Alcohol dependence is a complex disorder that initiates with episodes of excessive alcohol drinking known as binge drinking. It has a 50-60% risk contribution from inherited susceptibility genes; however, their exact identity and function are still poorly understood. We report that alcohol-prefer...

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Source

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Identifiers

PMID: 25567426
DOI: 10.1038/npp.2015.4
PMCID: PMC4397415

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25567426-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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