Article
Drug eruptions induced by allopurinol associated with HLA-B*5801.
Indian journal of dermatology, venereology and leprology - 1 Jan 2000
Zeng Meihua, Zhang Min, Liu Fang, Yan Wenliang, Kong Qingtao, Sang Hong
Abstract excerpt
Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA-BFNx015801 allele is a very strong marker for allopurinol-induced cutaneous adverse drug reactions (cADRs). In this article we report two cases of allopurinol-induced drug eruptions in patients carrying the HLA-BFNx015801 allele and review the literature on the...
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