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Article

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects.

Nature communications - 14 Jun 2021

Choquet Hélène, Melles Ronald B, Anand Deepti, Yin Jie, Cuellar-Partida Gabriel, Wang Wei, Hoffmann Thomas J, Nair K Saidas, Hysi Pirro G, Lachke Salil A, Jorgenson Eric

Abstract excerpt

Cataract is the leading cause of blindness among the elderly worldwide and cataract surgery is one of the most common operations performed in the United States. As the genetic etiology of cataract formation remains unclear, we conducted a multiethnic genome-wide association meta-analysis, combining results from the GERA and UK Biobank cohorts, and tested for replication in the 23andMe research cohort. We report...

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Identifiers

PMID: 34127677
DOI: 10.1038/s41467-021-23873-8
PMCID: PMC8203611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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