Article
Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder.
The Journal of clinical psychiatry - 1 Feb 2015
Byrne Enda M, Raheja Uttam K, Stephens Sarah H, Heath Andrew C, Madden Pamela A F, Vaswani Dipika, Nijjar Gagan V, Ryan Kathleen A, Youssufi Hassaan, Gehrman Philip R, Shuldiner Alan R, Martin Nicholas G, Montgomery Grant W, Wray Naomi R, Nelson Elliot C, Mitchell Braxton D, Postolache Teodor T
Abstract excerpt
OBJECTIVE: To test common genetic variants for association with seasonality (seasonal changes in mood and behavior) and to investigate whether there are shared genetic risk factors between psychiatric disorders and seasonality. METHOD: Genome-wide association studies (GWASs) were conducted in Australian (between 1988 and 1990 and between 2010 and 2013) and Amish (between May 2010 and December 2011) samples in...
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