Article
Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia.
Bipolar disorders - 1 Nov 2009
Mansour Hader A, Talkowski Michael E, Wood Joel, Chowdari Kodavali V, McClain Lora, Prasad Konasale, Montrose Debra, Fagiolini Andrea, Friedman Edward S, Allen Michael H, Bowden Charles L, Calabrese Joseph, El-Mallakh Rif S, Escamilla Michael, Faraone Stephen V, Fossey Mark D, Gyulai Laszlo, Loftis Jennifer M, Hauser Peter, Ketter Terence A, Marangell Lauren B, Miklowitz David J, Nierenberg Andrew A, Patel Jayendra, Sachs Gary S, Sklar Pamela, Smoller Jordan W, Laird Nan, Keshavan Matcheri, Thase Michael E, Axelson David, Birmaher Boris, Lewis David, Monk Tim, Frank Ellen, Kupfer David J, Devlin Bernie, Nimgaonkar Vishwajit L
Abstract excerpt
OBJECTIVE: Published studies suggest associations between circadian gene polymorphisms and bipolar I disorder (BPI), as well as schizoaffective disorder (SZA) and schizophrenia (SZ). The results are plausible, based on prior studies of circadian abnormalities. As replications have not been attempted uniformly, we evaluated representative, common polymorphisms in all three disorders. METHODS: We assayed 276...
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