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Article

Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders.

Genome biology - 1 Jan 2014

Forni Diego, Pozzoli Uberto, Cagliani Rachele, Tresoldi Claudia, Menozzi Giorgia, Riva Stefania, Guerini Franca R, Comi Giacomo P, Bolognesi Elisabetta, Bresolin Nereo, Clerici Mario, Sironi Manuela

Abstract excerpt

BACKGROUND: The temporal coordination of biological processes into daily cycles is a common feature of most living organisms. In humans, disruption of circadian rhythms is commonly observed in psychiatric diseases,including schizophrenia, bipolar disorder, depression and autism. Light therapy is the most effective treatment for seasonal affective disorder and circadian-related treatments sustain antidepressant...

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Identifiers

PMID: 25358694
DOI: 10.1186/s13059-014-0499-7
PMCID: PMC4237747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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