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Article

Association of CLOCK, ARNTL, and NPAS2 gene polymorphisms and seasonal variations in mood and behavior.

Chronobiology international - 1 Jan 2015

Kim Hae-In, Lee Heon-Jeong, Cho Chul-Hyun, Kang Seung-Gul, Yoon Ho-Kyoung, Park Young-Min, Lee Seung-Hwan, Moon Joung-Ho, Song Hye-Min, Lee Eunil, Kim Leen

Abstract excerpt

Seasonal affective disorder (SAD) is a condition of seasonal mood changes characterized by recurrent depression in autumn or winter that spontaneously remits in spring or summer. Evidence has suggested that circadian gene variants contribute to the pathogenesis of SAD. In this study, we investigated polymorphisms in the CLOCK, ARNTL, and NPAS2 genes in relation to seasonal variation in 507 healthy young adults....

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Source

Identifiers

PMID: 26134245
DOI: 10.3109/07420528.2015.1049613

Genes

CLOCK
NPAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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