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Article

Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants.

Scientific reports - 25 May 2021

Repar Jelena, Zahradka Davor, Sović Ivan, Zahradka Ksenija

Abstract excerpt

Genome stability in radioresistant bacterium Deinococcus radiodurans depends on RecA, the main bacterial recombinase. Without RecA, gross genome rearrangements occur during repair of DNA double-strand breaks. Long repeated (insertion) sequences have been identified as hot spots for ectopic recombination leading to genome rearrangements, and single-strand annealing (SSA) postulated to be the most likely mechanism...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34035321
DOI: 10.1038/s41598-021-89173-9
PMCID: PMC8149714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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