Article
QTL on mouse chromosomes 1 and 4 causing sperm-head morphological abnormality and male subfertility.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2012
Gotoh Hideo, Hirawatari Keitaro, Hanzawa Naoto, Miura Ikuo, Wakana Shigeharu
Abstract excerpt
The B10.M mouse strain represents a model for male subfertility as it produces a significantly low number of offspring. The only known male reproductive phenotype of this strain is its high frequency of sperm-head morphological abnormalities (44.7 ± 2.4 %). We previously reported that this phenotype was the product of two recessive loci. In this study we mapped the loci causing the high frequency of sperm-head...
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