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Article

NLRP1 L155H Polymorphism is a Risk Factor for Preeclampsia Development.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jun 2015

Pontillo Alessandra, Reis Edione C, Bricher Pamela N, Vianna Priscila, Diniz Solange, Fernandes Karla S, Chies Jose A, Sandrim Valeria

Abstract excerpt

PROBLEM: Augmented levels of IL-1ß have been pointed out as an important pathogenic factor for preeclampsia development. Inflammasome is the cytoplasmic complex responsible for pro-IL1ß cleavage and IL-1ß secretion. Aim of the study was to evaluate the association between polymorphisms in inflammasome' genes and preeclampsia. METHOD OF STUDY: Selected polymorphisms in inflammasome genes (NLRP1, NLRP3, CARD8, and...

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Source

Identifiers

PMID: 25556596
DOI: 10.1111/aji.12353

Genes

NLRP1
CARD8
NLRP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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