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Article

A clear and present danger: inflammasomes DAMPing down disorders of pregnancy

17 Nov 2014

Abstract excerpt

BACKGROUND: When the normal progression of pregnancy is threatened, inflammatory processes are often amplified in order to minimize detrimental effects and eliminate noxious agents. Inflammasomes are unique, intracellular, multiprotein assemblies that enable caspase-1 mediated proteolytic processing of the proinflammatory cytokine interleukin-1β, levels of which are elevated in some forms of preterm birth and...

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Share to Inflammasome and immune disorders
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PMID: 25403436
DOI: 10.1093/humupd/dmu059

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