Article
Clinicopathological significance of SNPs in RAD51 and XRCC3 in oral and oropharyngeal carcinomas.
Oral diseases - 1 Jan 2019
Santos Edilmar de Moura, Santos Hellen Bandeira de Pontes, de Matos Felipe Rodrigues, Machado Renato Assis, Coletta Ricardo D, Galvão Hébel Cavalcanti, Freitas Roseana de Almeida
Abstract excerpt
BACKGROUND: This study investigated the influence of single nucleotide polymorphisms (SNP) in RAD51 and XRCC3 on susceptibility to oral and oropharyngeal squamous cell carcinomas (SCC) and determined their clinicopathological significance. SUBJECTS AND METHODS: SNPs rs1801320 and rs1801321 in RAD51 and rs861539 in XRCC3 were genotyped in 81 patients presenting oral SCC, 45 presenting oropharyngeal SCC, and 130...
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