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Article

Genetic variability of Xrcc3 and Rad51 modulates the risk of head and neck cancer.

Gene - 10 Aug 2012

Gresner Peter, Gromadzinska Jolanta, Polanska Kinga, Twardowska Ewa, Jurewicz Joanna, Wasowicz Wojciech

Abstract excerpt

A case-control study was conducted to analyze the possible associations between the head and neck cancer (HNC) risk and fourteen single nucleotide polymorphisms (SNPs) and haplotypes in Xrcc3 and Rad51 genes. This study involved 81 HNC cases and 111 healthy control subjects. A significant risk-increasing effect of rs3212057 (p.Arg94His) SNP in Xrcc3 (OR=6.6; p<0.01) was observed. On the other hand,...

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Source

Identifiers

PMID: 22613844
DOI: 10.1016/j.gene.2012.05.030

Variants

rs3212057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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