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The RUNX Family, a Novel Multifaceted Guardian of the Genome

7 Jan 2023

Abstract excerpt

The DNA repair machinery exists to protect cells from daily genetic insults by orchestrating multiple intrinsic and extrinsic factors. One such factor recently identified is the Runt-related transcription factor (RUNX) family, a group of proteins that act as a master transcriptional regulator for multiple biological functions such as embryonic development, stem cell behaviors, and oncogenesis. A significant...

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PMID: 36672189
DOI: 10.3390/cells12020255

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