Article
The clinical significance of serrated polyps.
The American journal of gastroenterology - 1 Feb 2011
Huang Christopher S, Farraye Francis A, Yang Shi, O'Brien Michael J
Abstract excerpt
Colorectal cancer (CRC) is a heterogeneous disorder than arises via multiple distinct pathways, such as the serrated pathway, in which serrated polyps (including variants of hyperplastic polyps) are the precursor lesions. Approximately 15-20% of all CRCs arise via the serrated pathway, and these serrated carcinomas are clinically, morphologically, and molecularly distinct from conventional CRCs. The prevention of...
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